12/case — Directions: Apply generously to tooth brush & brush as normal or as directed by a dentist or doctor. For human use only. Xylitol is not good for dogs. — Ingredients: 22ppm SilverSol Solution (Deionized Water, Purified Silver), Xylitol, TEA, Carbomer, Peppermint Oil. No Triclosan, Glycerin, Fluoride, Parabens or SLS. Non-Abrasive/No BPA